SCHEMBL31334686

SCHEMBL31334686

O=C1CC[C@@H](Nc2ccc(N3CCC(N4CCC(NC(=O)OCc5ccccc5)CC4)CC3)c(F)c2)C(=O)N1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 6/20 0.41
CRBN Q96SW2 6/20 0.41
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
CTSL P07711 1/20 0.39
CTSB P07858 1/20 0.39
CTSK P43235 1/20 0.39
ALDH1A1 P00352 1/20 0.38
GAA P10253 1/20 0.38
F13A1 P00488 1/20 0.38
TGM2 P21980 1/20 0.38
TGM1 P22735 1/20 0.38
GPR55 Q9Y2T6 2/20 0.38
GRM5 P41594 1/20 0.38
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30965538 0.89 CHRM4 (0.45) DDB1CRBNMEN1KMT2AF13A1
SCHEMBL30136056 0.87 DDB1 (0.41) DDB1CRBNMEN1KMT2ACTSL
SCHEMBL31333516 0.81 DDB1 (0.47) DDB1CRBNMEN1KMT2A
SCHEMBL29744905 0.81 CRBN (0.44) DDB1CRBNMEN1KMT2AGRM5
SCHEMBL29744735 0.81 CRBN (0.44) DDB1CRBNMEN1KMT2AGRM5
SCHEMBL23538648 0.81 CRBN (0.44) DDB1CRBNMEN1KMT2AGRM5
SCHEMBL23538726 0.81 CRBN (0.44) DDB1CRBNMEN1KMT2AGRM5
SCHEMBL29946989 0.81 CRBN (0.44) DDB1CRBNMEN1KMT2AGRM5
SCHEMBL29744637 0.81 CRBN (0.44) DDB1CRBNMEN1KMT2AGRM5
SCHEMBL31334245 0.81 CRBN (0.44) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed