Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | DYRK2 | Q92630 | 5/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | CCND3 | P30281 | 1/20 | 0.36 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.36 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.35 |
| ▸ | CBL | P22681 | 1/20 | 0.34 |
| ▸ | CBLB | Q13191 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333259 | 0.91 | MAPK1 (0.42) | MAPK1DYRK2CDK4CCND1CCND3 | |
| SCHEMBL31333858 | 0.90 | MAPK3 (0.41) | MAPK1ROCK2ROCK1CCNA2CDK2 | |
| SCHEMBL31333877 | 0.89 | CDK2 (0.40) | MAPK1ROCK2ROCK1CCNA2CDK2 | |
| SCHEMBL31333814 | 0.89 | MAPK1 (0.45) | MAPK1DYRK2CDK4CCND1CCND3 | |
| SCHEMBL31333223 | 0.89 | MAPK1 (0.45) | MAPK1DYRK2CDK4CCND1CCND3 | |
| SCHEMBL31334023 | 0.85 | MAPK1 (0.39) | MAPK1CDK4CCND1CCND3CDK6 | |
| SCHEMBL31333236 | 0.83 | SYK (0.38) | MAPK1CDK4CCND1CCND3CDK6 | |
| SCHEMBL31334568 | 0.82 | KDM1A (0.39) | MAPK1CDK4CCND1CCND3CDK6 | |
| SCHEMBL31334506 | 0.82 | MAPK3 (0.40) | MAPK1CDK4CCND1CCND3CDK6 | |
| SCHEMBL31333431 | 0.82 | SYK (0.43) | MAPK1DYRK2CDK4CCND1CCND3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |