Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.42 |
| ▸ | CDK2 | P24941 | 3/20 | 0.40 |
| ▸ | MAPK3 | P27361 | 3/20 | 0.40 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 4/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334417 | 0.95 | MAPK1 (0.41) | MAPK1CDK2MAPK3CAMK1DCCNA2 | |
| SCHEMBL31334975 | 0.95 | MAPK1 (0.41) | MAPK1CDK2MAPK3CAMK1DCCNA2 | |
| SCHEMBL31333839 | 0.92 | MAPK1 (0.42) | MAPK1CDK2MAPK3CAMK1DCCNA2 | |
| SCHEMBL31333553 | 0.90 | MAPK1 (0.42) | MAPK1CDK2MAPK3CCNA2CDK1 | |
| SCHEMBL31334329 | 0.90 | CDK9 (0.42) | MAPK1CDK2MAPK3CAMK1DCCNA2 | |
| SCHEMBL31334455 | 0.90 | CDK9 (0.42) | MAPK1CDK2MAPK3CAMK1DCCNA2 | |
| SCHEMBL31334836 | 0.89 | MAP4K1 (0.43) | MAPK1CDK2MAPK3CCNA2CDK1 | |
| SCHEMBL31333902 | 0.89 | MAP4K1 (0.43) | MAPK1CDK2MAPK3CCNA2CDK1 | |
| SCHEMBL31334173 | 0.88 | MAPK1 (0.42) | MAPK1CDK2MAPK3CAMK1DCCNA2 | |
| SCHEMBL31333597 | 0.88 | MAPK1 (0.41) | MAPK1CDK2MAPK3CCNA2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |