Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.41 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.38 |
| ▸ | CDK2 | P24941 | 4/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.38 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333644 | 0.89 | JAK2 (0.45) | SYKPCSK9MAPK1CDK2CCNA2 | |
| SCHEMBL31334302 | 0.88 | CCNT1 (0.43) | SYKPCSK9MAPK1CDK2CCNA2 | |
| SCHEMBL31333464 | 0.86 | ADORA1 (0.41) | MAPK1CDK2CCNA2MAPK3JAK2 | |
| SCHEMBL31333190 | 0.84 | PCSK9 (0.44) | SYKPCSK9MAPK1CDK2CCNA2 | |
| SCHEMBL31333363 | 0.84 | ADORA1 (0.48) | SYKPCSK9MAPK1CDK2CCNA2 | |
| SCHEMBL31333852 | 0.84 | SYK (0.46) | SYKPCSK9MAPK1CDK2CCNA2 | |
| SCHEMBL31333776 | 0.81 | SYK (0.46) | SYKPCSK9MAPK1CDK2CCNA2 | |
| SCHEMBL31333268 | 0.81 | SYK (0.46) | SYKPCSK9MAPK1CDK2CCNA2 | |
| SCHEMBL31334910 | 0.81 | SYK (0.46) | SYKPCSK9MAPK1CDK2CCNA2 | |
| SCHEMBL31334462 | 0.81 | SYK (0.44) | SYKPCSK9MAPK1CDK2CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |