Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.40 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.39 |
| ▸ | DYRK2 | Q92630 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333264 | 0.90 | SYK (0.46) | SYKROCK2ROCK1PCSK9MAPK1 | |
| SCHEMBL31333683 | 0.90 | SYK (0.46) | SYKROCK2ROCK1PCSK9MAPK1 | |
| SCHEMBL31333586 | 0.90 | SYK (0.46) | SYKROCK2ROCK1PCSK9MAPK1 | |
| SCHEMBL31333461 | 0.89 | SYK (0.48) | SYKROCK2ROCK1PCSK9MAPK1 | |
| SCHEMBL31334113 | 0.89 | SYK (0.39) | SYKROCK2ROCK1PCSK9DYRK2 | |
| SCHEMBL31333294 | 0.89 | SYK (0.39) | SYKROCK2ROCK1PCSK9DYRK2 | |
| SCHEMBL31333260 | 0.87 | SYK (0.43) | SYKROCK2ROCK1PCSK9MAPK1 | |
| SCHEMBL31334025 | 0.87 | SYK (0.38) | SYKROCK2ROCK1PCSK9DYRK2 | |
| SCHEMBL31333513 | 0.86 | MAPK1 (0.43) | SYKPCSK9DYRK2MAPK1CCNA2 | |
| SCHEMBL31333363 | 0.86 | ADORA1 (0.48) | SYKPCSK9MAPK1CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |