Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.42 |
| ▸ | MAPK3 | P27361 | 3/20 | 0.41 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.39 |
| ▸ | CDK2 | P24941 | 3/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 3/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333683 | 1.00 | SYK (0.46) | SYKROCK2ROCK1MAPK3PCSK9 | |
| SCHEMBL31333586 | 1.00 | SYK (0.46) | SYKROCK2ROCK1MAPK3PCSK9 | |
| SCHEMBL31333461 | 0.92 | SYK (0.48) | SYKROCK2ROCK1MAPK3PCSK9 | |
| SCHEMBL31334910 | 0.92 | SYK (0.46) | SYKROCK2ROCK1MAPK3PCSK9 | |
| SCHEMBL31333260 | 0.91 | SYK (0.43) | SYKROCK2ROCK1MAPK3PCSK9 | |
| SCHEMBL31333776 | 0.91 | SYK (0.46) | SYKMAPK3PCSK9MAPK1CCNA2 | |
| SCHEMBL31333268 | 0.91 | SYK (0.46) | SYKMAPK3PCSK9MAPK1CCNA2 | |
| SCHEMBL31333360 | 0.90 | MAPK3 (0.48) | SYKROCK2ROCK1MAPK3PCSK9 | |
| SCHEMBL31334801 | 0.90 | SYK (0.42) | SYKROCK2ROCK1MAPK3PCSK9 | |
| SCHEMBL31334914 | 0.89 | ROCK2 (0.45) | SYKROCK2ROCK1MAPK3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |