SCHEMBL31334820

SCHEMBL31334820

O=C1CCC(Nc2ccc(N3CCC(N4CCC(NC(=O)[C@H]5CC[C@H](Nc6ncc(F)c(-c7cccc(N8CCCCC8=O)c7)n6)CC5)CC4)C(F)C3)c(F)c2)C(=O)N1

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SYK P43405 3/20 0.34
FPR2 P25090 1/20 0.33
CCNT1 O60563 1/20 0.32
CCNK O75909 1/20 0.32
CCNA2 P20248 1/20 0.32
CDK2 P24941 1/20 0.32
CDK7 P50613 1/20 0.32
CDK9 P50750 1/20 0.32
CCNH P51946 1/20 0.32
CDK13 Q14004 1/20 0.32
CDK12 Q9NYV4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31335053 0.98 SYK (0.34) SYKFPR2CCNT1CCNKCCNA2
SCHEMBL31333209 0.94 CCNT1 (0.34) SYKCCNT1CCNKCCNA2CDK2
SCHEMBL31334689 0.93 BTK (0.32) CCNT1CCNKCCNA2CDK2CDK7
SCHEMBL31333594 0.92 CCNT1 (0.32) CCNT1CCNKCCNA2CDK2CDK7
SCHEMBL31333976 0.92 CCNT1 (0.34) SYKCCNT1CCNKCCNA2CDK2
SCHEMBL31334774 0.92 CDK4 (0.36) SYKFPR2CCNT1CCNKCCNA2
SCHEMBL31333456 0.91 BTK (0.32) CCNT1CCNKCCNA2CDK2CDK7
SCHEMBL31334525 0.91 CCNT1 (0.33) CCNT1CCNKCCNA2CDK2CDK7
SCHEMBL31333276 0.90 CDK4 (0.36) SYKFPR2CCNT1CCNKCCNA2
SCHEMBL31333880 0.90 CCNT1 (0.32) SYKCCNT1CCNKCCNA2CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed