Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 7/20 | 0.56 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 10/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 9/20 | 0.48 |
| ▸ | MAPK9 | P45984 | 9/20 | 0.48 |
| ▸ | JUN | P05412 | 8/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.48 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | ACACA | Q13085 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 2/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.47 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333215 | 0.95 | MAPK1 (0.59) | MAPK1MAPK3CDK2MAPK8MAPK9 | |
| SCHEMBL31335038 | 0.93 | CDK2 (0.54) | MAPK1CDK2MAPK8MAPK9JUN | |
| SCHEMBL31334708 | 0.92 | MAPK1 (0.51) | MAPK1MAPK3CDK2MAPK8MAPK9 | |
| SCHEMBL31334722 | 0.90 | MAPK1 (0.53) | MAPK1CDK2MAPK8MAPK9JUN | |
| SCHEMBL31333479 | 0.88 | MAPK1 (0.49) | MAPK1CDK2MAPK8MAPK9JUN | |
| SCHEMBL31334010 | 0.88 | MAPK1 (0.49) | MAPK1CDK2MAPK8MAPK9JUN | |
| SCHEMBL31334616 | 0.88 | MAPK8 (0.51) | MAPK1CDK2MAPK8MAPK9JUN | |
| SCHEMBL31334204 | 0.88 | MAPK1 (0.57) | MAPK1MAPK3CDK2MAPK8MAPK9 | |
| SCHEMBL31334027 | 0.88 | MAPK1 (0.51) | MAPK1CDK2MAPK8MAPK9JUN | |
| SCHEMBL31335001 | 0.87 | MAPK8 (0.51) | MAPK1CDK2MAPK8MAPK9JUN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |