SCHEMBL31334935

SCHEMBL31334935

O=C1CCC(N2Cc3cc(OC4CCN(CC5CCN(CC(=O)N6CCC(Nc7ncc(Cl)c(-c8cccc(-c9ccccc9)c8)n7)CC6)CC5)CC4)ccc3C2=O)C(=O)N1

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 16/20 0.44
CRBN Q96SW2 2/20 0.41
ESR1 P03372 1/20 0.41
IKZF2 Q9UKS7 1/20 0.41
ALK Q9UM73 1/20 0.41
BTK Q06187 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31333659 0.94 MAPK1 (0.44) MAPK1
SCHEMBL31333740 0.94 MAPK1 (0.44) MAPK1BTK
SCHEMBL31333691 0.91 MAPK1 (0.42) MAPK1CRBNESR1IKZF2ALK
SCHEMBL31333199 0.90 MAPK1 (0.42) MAPK1BTK
SCHEMBL31333647 0.89 MAPK1 (0.44) MAPK1BTK
SCHEMBL31334627 0.89 MAPK1 (0.41) MAPK1BTK
SCHEMBL31334853 0.87 MAPK1 (0.43) MAPK1IKZF2
SCHEMBL31334654 0.86 MAPK1 (0.41) MAPK1CRBNESR1IKZF2BTK
SCHEMBL31334745 0.85 MAPK1 (0.42) MAPK1CRBNIKZF2BTK
SCHEMBL31334864 0.84 IKZF1 (0.52) MAPK1IKZF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed