Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.47 |
| ▸ | AXL | P30530 | 2/20 | 0.47 |
| ▸ | MERTK | Q12866 | 1/20 | 0.47 |
| ▸ | BPTF | Q12830 | 1/20 | 0.45 |
| ▸ | PNMT | P11086 | 3/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | MELK | Q14680 | 1/20 | 0.42 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31335858 | 0.92 | DDB1 (0.44) | POLBDDB1CRBNTYRO3AXL | |
| SCHEMBL10269075 | 0.88 | POLB (0.55) | POLBDDB1CRBNTYRO3AXL | |
| SCHEMBL6898991 | 0.80 | POLB (0.53) | POLBDDB1CRBNAXL | |
| SCHEMBL12853748 | 0.76 | POLB (0.58) | POLBAXL | |
| SCHEMBL10061741 | 0.76 | POLB (0.48) | POLBDDB1CRBNTYRO3AXL | |
| SCHEMBL10268414 | 0.74 | PDK2 (0.46) | DDB1CRBNTYRO3AXLMERTK | |
| SCHEMBL12386017 | 0.74 | PNMT (0.55) | PNMTADRA2AADRA2BADRA2CMELK | |
| SCHEMBL29586931 | 0.74 | PNMT (0.55) | PNMTADRA2AADRA2BADRA2CMELK | |
| SCHEMBL12853758 | 0.72 | PDK2 (0.54) | POLBDDB1CRBNTYRO3AXL | |
| SCHEMBL19339193 | 0.72 | POLB (0.54) | POLBAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |