Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17686920 | 0.88 | DDB1 (0.47) | DDB1CRBNNAMPTMAPK1HDAC1 | |
| SCHEMBL31335950 | 0.88 | DDB1 (0.47) | DDB1CRBNNAMPTMAPK1HDAC1 | |
| SCHEMBL31335976 | 0.87 | NAMPT (0.54) | DDB1CRBNNAMPTMAPK1UCHL1 | |
| SCHEMBL16269644 | 0.86 | DDB1 (0.45) | DDB1CRBNNAMPTMAPK1HDAC1 | |
| SCHEMBL31013975 | 0.86 | DDB1 (0.46) | DDB1CRBNNAMPTMAPK1HDAC1 | |
| SCHEMBL31335890 | 0.86 | ACHE (0.48) | DDB1CRBNNAMPTMAPK1UCHL1 | |
| SCHEMBL15893731 | 0.86 | DDB1 (0.52) | DDB1CRBNNAMPTMAPK1HDAC1 | |
| SCHEMBL31013972 | 0.86 | DDB1 (0.52) | DDB1CRBNNAMPTMAPK1HDAC1 | |
| SCHEMBL18422662 | 0.84 | DDB1 (0.47) | DDB1CRBNNAMPTMAPK1HDAC1 | |
| SCHEMBL31335944 | 0.83 | HTT (0.48) | DDB1CRBNNAMPTMAPK1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |