Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.45 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.45 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.45 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.45 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.45 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.45 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26125227 | 1.00 | HDAC1 (0.58) | HDAC1HDAC6KDM4EPRKAB2PRKAG1 | |
| SCHEMBL34463628 | 0.82 | SMYD3 (0.38) | HDAC1HDAC6KDM4EALDH1A1GAA | |
| SCHEMBL22117005 | 0.79 | TRPV1 (0.41) | HDAC1HDAC6 | |
| SCHEMBL31375577 | 0.78 | ALDH1A1 (0.70) | HDAC1HDAC6KDM4EALDH1A1MAPT | |
| SCHEMBL11921493 | 0.75 | HDAC1 (0.58) | HDAC1HDAC6KDM4EPRKAB2PRKAG1 | |
| SCHEMBL18027923 | 0.75 | KDM4E (0.60) | HDAC1HDAC6KDM4EPRKAB2PRKAG1 | |
| SCHEMBL18742440 | 0.75 | NPC1 (0.34) | HDAC1HDAC6KDM4EALDH1A1MAPT | |
| SCHEMBL28923985 | 0.75 | ALDH1A1 (0.44) | KDM4EALDH1A1GAAPOLBNPC1 | |
| SCHEMBL3952478 | 0.74 | HDAC6 (0.72) | HDAC1HDAC6KDM4EPRKAB2PRKAG1 | |
| SCHEMBL14327631 | 0.74 | HDAC6 (1.00) | HDAC1HDAC6KDM4EPRKAB2PRKAG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119212707-A | Oxadiazole HDAC6 inhibitors and uses thereof | 艾科尼佐治疗股份有限公司 | 2024-12-27 | — | — | CN | disclosed |