Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 11/20 | 0.51 |
| ▸ | GRM1 | Q13255 | 11/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | CDK9 | P50750 | 2/20 | 0.49 |
| ▸ | WNT3A | P56704 | 1/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.49 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8512618 | 1.00 | GRM5 (0.51) | GRM5GRM1NAMPTCDK9WNT3A | |
| SCHEMBL26074128 | 0.88 | GRM5 (0.43) | GRM5GRM1NAMPTCDK9WNT3A | |
| SCHEMBL30545737 | 0.88 | GRM5 (0.43) | GRM5GRM1NAMPTCDK9WNT3A | |
| SCHEMBL31227073 | 0.87 | WNT3A (0.61) | GRM5GRM1NAMPTCDK9WNT3A | |
| SCHEMBL171730 | 0.87 | WNT3A (0.61) | GRM5GRM1NAMPTCDK9WNT3A | |
| SCHEMBL30796996 | 0.87 | GRM1 (0.49) | GRM5GRM1NAMPTCDK9WNT3A | |
| SCHEMBL29580742 | 0.86 | GRM1 (0.52) | GRM5GRM1NAMPTCDK9WNT3A | |
| SCHEMBL30796705 | 0.86 | GRM1 (0.51) | GRM5GRM1NAMPTCDK9WNT3A | |
| SCHEMBL22324775 | 0.86 | GRM1 (0.52) | GRM5GRM1NAMPTCDK9WNT3A | |
| SCHEMBL27461432 | 0.86 | GRM1 (0.51) | GRM5GRM1NAMPTCDK9WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250051343-A1 | INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES | Isosterix, Inc. | 2025-02-13 | — | — | US | disclosed |
| CN-119301096-A | Inhibitors of MYST family lysine acetyltransferase | 伊索斯泰里克斯公司 | 2025-01-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250051343-A1 | INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES | KAT6A, KAT6B, KAT2A | GRM5 4065/4885GRM1 4103/4885NAMPT 507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.