SCHEMBL31336271

SCHEMBL31336271

C=CC(=O)NCCNC(=O)c1ccc(B(O)O)cc1F

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ESRRG P62508 1/20 0.37
KDM4E B2RXH2 1/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
BTK Q06187 2/20 0.35
GAA P10253 1/20 0.34
HPGD P15428 1/20 0.34
HDAC3 O15379 1/20 0.34
TMEM97 Q5BJF2 1/20 0.34
SIGMAR1 Q99720 1/20 0.34
ALDH1A1 P00352 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
MAP2K2 P36507 1/20 0.33
MAP2K1 Q02750 1/20 0.33
MAPK3 P27361 1/20 0.33
TGM2 P21980 1/20 0.33
MCHR1 Q99705 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13644470 1.00 ESRRG (0.37) ESRRGKDM4ENPC1RAB9ABTK
SCHEMBL31336270 1.00 ESRRG (0.37) ESRRGKDM4ENPC1RAB9ABTK
SCHEMBL26617008 0.84 TGM2 (0.34) GAAHPGDALDH1A1TGM2
SCHEMBL26617010 0.84 TGM2 (0.38) RAB9AGAAHPGDALDH1A1TGM2
SCHEMBL26617009 0.84 HPGD (0.47) ESRRGKDM4ENPC1RAB9AHPGD
SCHEMBL14743123 0.82 MAP2K2 (0.47) ESRRGKDM4ENPC1RAB9AHPGD
SCHEMBL13644472 0.82 MAOB (0.41) ESRRGKDM4ENPC1RAB9AHDAC3
SCHEMBL30672963 0.81 MEN1 (0.37) ESRRGNPC1RAB9ABTKTMEM97
Hydrochloric Acid SCHEMBL23827734 0.81 PMP22 (0.42) ESRRGKDM4ENPC1RAB9AHDAC3
Hydrochloric Acid SCHEMBL30152034 0.81 PMP22 (0.42) ESRRGKDM4ENPC1RAB9AHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024232325-A1 DIOXAZABOROCANE DERIVATIVE 国立大学法人 東京医科歯科大学 2024-11-14 WO disclosed