SCHEMBL3133638

SCHEMBL3133638

O=C(Oc1ccccc1)C1CCNCC1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.58
HTT P42858 1/20 0.56
KMT2A Q03164 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
POLB P06746 2/20 0.54
L3MBTL1 Q9Y468 1/20 0.53
HRH1 P35367 2/20 0.50
ALDH1A1 P00352 1/20 0.47
GABRP O00591 1/20 0.45
GABRD O14764 1/20 0.45
GABRA1 P14867 1/20 0.45
TSHR P16473 1/20 0.45
GABRB1 P18505 1/20 0.45
GABRG2 P18507 1/20 0.45
GABRB3 P28472 1/20 0.45
GABRA5 P31644 1/20 0.45
GABRA3 P34903 1/20 0.45
GABRA2 P47869 1/20 0.45
GABRB2 P47870 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL21410019 0.98 ELANE (0.57) ELANEHTTKMT2ASMN1; SMN2TDP1
Hydrochloric Acid SCHEMBL28125954 0.98 ELANE (0.57) ELANEHTTKMT2ASMN1; SMN2TDP1
SCHEMBL5813373 0.90 ELANE (0.51) ELANEHTTKMT2ASMN1; SMN2TDP1
SCHEMBL28167146 0.90 ELANE (0.51) ELANEHTTKMT2ASMN1; SMN2TDP1
SCHEMBL3079124 0.87 ELANE (0.73) ELANEHTTKMT2ASMN1; SMN2TDP1
SCHEMBL12370828 0.87 ELANE (0.73) ELANEHTTKMT2ASMN1; SMN2TDP1
SCHEMBL12642500 0.87 ELANE (0.73) ELANEHTTKMT2ASMN1; SMN2TDP1
SCHEMBL3193624 0.87 ELANE (0.73) ELANEHTTKMT2ASMN1; SMN2TDP1
SCHEMBL525974 0.87 ELANE (0.73) ELANEHTTKMT2ASMN1; SMN2TDP1
Hydrochloric Acid SCHEMBL3866426 0.85 ELANE (0.71) ELANEHTTKMT2ASMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1193968-A 2,3-dioxo-1,2,3,4-tetrahydro-quinoyxalinyl derivatives NOVARTIS AG (CH) 1998-09-23 CN claimed
CN-105473585-B Piperidine carboxylic acid derivative as fungicide 拜耳作物科学股份公司 2018-04-13 CN disclosed
EP-2166018-A2 Antibody binding affinity ligands Novo Nordisk A/S (DK) 2010-03-24 EP disclosed
EP-1831243-B1 ANTIBODY BINDING AFFINITY LIGANDS NOVO NORDISK AS (DK) 2010-03-17 EP disclosed
US-20080311681-A1 Antibody Binding Affinity Ligands VERSAMATRIX A/S (DK) 2008-12-18 US disclosed
EP-1831243-A2 ANTIBODY BINDING AFFINITY LIGANDS Novo Nordisk A/S (DK) 2007-09-12 EP disclosed
WO-2006066598-A2 ANTIBODY BINDING AFFINITY LIGANDS NOVO NORDISK A/S (DK) 2006-06-29 WO disclosed
CN-1225489-C Photocurable composition, cured body, and method for producing same MITSUBISHI CHEM CORP (JP) 2005-11-02 CN disclosed
CN-1432029-A Photocurable composition, cured body, and method for producing same MITSUBISHI CHEM CORP (JP) 2003-07-23 CN disclosed
US-5869184-A RESIN RAW MATERIALS FOR PAINTS, ADHESIVES MITSUI TOATSU CHEMICALS, INC. (JP) 1999-02-09 US disclosed
US-5648446-A ADHESIVES, FIREPROOFING, HEAT RESISTANCE IN RESINS FOR MOLDING MATERIALS MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-15 US disclosed
US-5646240-A THERMOSETTING MOLDING COMPOSITIONS MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-08 US disclosed
US-5596039-A FLAME RETARDERS, HEAT RESISTANCE MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1997-01-21 US disclosed
US-5569726-A USEFUL IN FLAME-RETARDING, THERMAL STABILIZATION AND COMPATIBILIZATION OF RESINS AND IN THERMOSETTING MOLDING COMPOSITIONS MITSUI TOATSU CHEMICALS, INC. (JP) 1996-10-29 US disclosed
US-5545702-A THERMOSETTING RESIN COMPOSITION MITSUI TOATSU CHEMICALS, INC. (JP) 1996-08-13 US disclosed
US-5536795-A ADHESIVES AND PAINTS AND FIREPROOFING THERMOSETTING RESINS MITSUI TOATSU CHEMICALS, INC. (JP) 1996-07-16 US disclosed
US-5480947-A N-METHYLOL DIGUANAMINES MITSUI TOATSU CHEMICALS, INC. (JP) 1996-01-02 US disclosed
EP-0612797-A2 Modification method of resins MITSUI TOATSU CHEMICALS, Inc. (JP) 1994-08-31 EP disclosed
US-4623685-A 1-PHENOXYCARBONYL-2,2,6,6-TETRAMETHYLPIPERIDYL COMPOUND ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1986-11-18 US disclosed
EP-0000167-A1 1,2,3,6-Tetrahydroisonicotinic acid and derivatives thereof, methods and starting products for their preparation, and pharmaceutical compositions containing them. Krogsgaard-Larsen, Povl (DK) 1979-01-10 EP disclosed