Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 10/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16994160 | 0.78 | CHRM2 (0.36) | NR1H2HDAC8 | |
| SCHEMBL16224360 | 0.78 | CHRM2 (0.36) | NR1H2HDAC8 | |
| SCHEMBL10281624 | 0.78 | CHRM2 (0.36) | NR1H2HDAC8 | |
| SCHEMBL35211182 | 0.78 | NR1H2 (0.43) | NR1H2TACR1 | |
| SCHEMBL703953 | 0.77 | NR1H2 (0.40) | NR1H2HDAC8TACR1 | |
| SCHEMBL17001728 | 0.77 | NR1H2 (0.40) | NR1H2HDAC8TACR1 | |
| SCHEMBL703952 | 0.77 | NR1H2 (0.40) | NR1H2HDAC8TACR1 | |
| SCHEMBL12424302 | 0.76 | NR1H2 (0.35) | NR1H2HDAC8 | |
| SCHEMBL704921 | 0.74 | NR1H2 (0.34) | NR1H2HDAC8 | |
| SCHEMBL704922 | 0.74 | NR1H2 (0.34) | NR1H2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688154-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - Portela & Ca., S.A. (PT) | 2026-02-11 | — | — | EP | claimed |
| WO-2025023851-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | claimed |
| EP-4688154-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - Portela & Ca., S.A. (PT) | 2026-02-11 | — | — | EP | disclosed |
| WO-2025023851-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | disclosed |