Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 4/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TNF | P01375 | 1/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.50 |
| ▸ | CCNC | P24863 | 1/20 | 0.49 |
| ▸ | CDK8 | P49336 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PDE5A | O76074 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23598961 | 1.00 | LMNA (0.58) | LMNANPC1HPGDCASP3RAB9A | |
| SCHEMBL31337018 | 0.94 | ESR1 (0.65) | LMNANPC1HPGDCASP3RAB9A | |
| SCHEMBL23598886 | 0.94 | ESR1 (0.65) | LMNANPC1HPGDCASP3RAB9A | |
| SCHEMBL23579700 | 0.91 | HIF1A (0.60) | LMNANPC1HPGDCASP3RAB9A | |
| SCHEMBL30034730 | 0.91 | HIF1A (0.60) | LMNANPC1HPGDCASP3RAB9A | |
| SCHEMBL28855649 | 0.91 | NPC1 (0.63) | LMNANPC1HPGDCASP3RAB9A | |
| SCHEMBL23579729 | 0.91 | NPC1 (0.59) | LMNANPC1HPGDCASP3RAB9A | |
| SCHEMBL30033923 | 0.91 | NPC1 (0.59) | LMNANPC1HPGDCASP3RAB9A | |
| SCHEMBL31336855 | 0.90 | NPC1 (0.54) | LMNANPC1HPGDCASP3RAB9A | |
| SCHEMBL28855513 | 0.90 | NPC1 (0.54) | LMNANPC1HPGDCASP3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151550-B | External nucleotide pyrophosphatase/phosphodiesterase 1 (ENPP 1) modulators and uses thereof | 桑福德·伯纳姆·普雷比医学发现研究所 | 2024-11-22 | — | — | CN | disclosed |