SCHEMBL31337409

SCHEMBL31337409

Nc1nc(N2CC3(COC3)C2)ns1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GAK O14976 1/20 0.35
DYRK1A Q13627 1/20 0.33
KCNQ3 O43525 1/20 0.33
KCNQ2 O43526 1/20 0.33
CHRM4 P08173 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL31467648 0.71 GAA (0.47)
SCHEMBL31214557 0.69 GAA (0.57)
SCHEMBL14688246 0.67 DYRK1A (0.39) DYRK1AKCNQ3KCNQ2CHRM4
SCHEMBL14880070 0.67 DYRK1A (0.51) GAKDYRK1A
SCHEMBL30988345 0.62 DYRK1A (0.41) DYRK1AKCNQ3KCNQ2CHRM4
SCHEMBL31696820 0.61 GRIN2D (0.45) DYRK1A
SCHEMBL25644836 0.61 DYRK1A (0.43) DYRK1AKCNQ3KCNQ2CHRM4
SCHEMBL14320347 0.59 HDAC4 (0.47)
SCHEMBL20548174 0.58 ADRA1A (0.40) DYRK1AKCNQ3KCNQ2CHRM4
SCHEMBL31493108 0.58 AR (0.37) CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4741390-A1 BIARYL RING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF Hangzhou Synrx Therapeutics Biomedical Technology Co., Ltd. (CN) 2026-05-13 EP disclosed
WO-2025045248-A1 BIARYL RING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF 杭州圣域生物医药科技有限公司 2025-03-06 WO disclosed
CN-119552156-A Biaryl ring compound, intermediate thereof, preparation method and application 杭州圣域生物医药科技有限公司 2025-03-04 CN disclosed