Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 14/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 12/20 | 0.45 |
| ▸ | PDE4A | P27815 | 8/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3122570 | 0.96 | PDE4B (0.44) | PDE4DPDE4BPDE4APDE4CRXRA | |
| SCHEMBL3130890 | 0.93 | PDE4D (0.51) | PDE4DPDE4BPDE4APDE4CRXRA | |
| SCHEMBL3120806 | 0.91 | LTC4S (0.47) | PDE4DPDE4BPDE4APDE4CRXRA | |
| SCHEMBL3129575 | 0.90 | MRGPRX4 (0.40) | PDE4DPDE4BPDE4APDE4CRXRA | |
| SCHEMBL3122581 | 0.89 | PDE4D (0.45) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL3131075 | 0.86 | TSHR (0.46) | PDE4DPDE4BPDE4APDE4CRXRA | |
| SCHEMBL3121025 | 0.86 | PDE4B (0.50) | PDE4DPDE4BPDE4APDE4CRXRA | |
| SCHEMBL1157297 | 0.85 | PDE4D (0.54) | PDE4DPDE4BPDE4APDE4CRXRA | |
| SCHEMBL3132719 | 0.84 | PDE4D (0.44) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL3131505 | 0.83 | PDE4D (0.40) | PDE4DPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003084-A2 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |