Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 6/20 | 0.54 |
| ▸ | IKZF3 | Q9UKT9 | 6/20 | 0.54 |
| ▸ | IKZF2 | Q9UKS7 | 10/20 | 0.53 |
| ▸ | IKZF1 | Q13422 | 4/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31352929 | 0.92 | CRBN (0.48) | CRBNIKZF3IKZF2IKZF1HSD11B1 | |
| SCHEMBL31338359 | 0.90 | IKZF2 (0.59) | CRBNIKZF3IKZF2IKZF1 | |
| SCHEMBL31338084 | 0.88 | CRBN (0.58) | CRBNIKZF3IKZF2IKZF1 | |
| SCHEMBL31352933 | 0.88 | CRBN (0.48) | CRBNIKZF3IKZF2IKZF1HSD11B1 | |
| SCHEMBL31338009 | 0.86 | HSD11B1 (0.53) | CRBNIKZF3HSD11B1 | |
| SCHEMBL31338230 | 0.86 | IKZF2 (0.59) | CRBNIKZF3IKZF2IKZF1 | |
| SCHEMBL24991553 | 0.85 | IKZF2 (0.59) | CRBNIKZF3IKZF2IKZF1 | |
| SCHEMBL31338112 | 0.85 | IKZF2 (0.57) | CRBNIKZF3IKZF2IKZF1 | |
| SCHEMBL25129767 | 0.85 | IKZF2 (0.59) | CRBNIKZF3IKZF2IKZF1 | |
| SCHEMBL30132160 | 0.85 | IKZF2 (0.59) | CRBNIKZF3IKZF2IKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4745137-A1 | GLUTARIMIDE ISOINDOLINONE SKELETON-BASED COMPOUND | Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) | 2026-05-20 | — | — | EP | claimed |
| WO-2025016359-A1 | GLUTARIMIDE ISOINDOLINONE SKELETON-BASED COMPOUND | 标新生物医药科技(上海)有限公司 | 2025-01-23 | — | — | WO | claimed |
| EP-4745137-A1 | GLUTARIMIDE ISOINDOLINONE SKELETON-BASED COMPOUND | Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) | 2026-05-20 | — | — | EP | disclosed |