SCHEMBL3133846

SCHEMBL3133846

CCCC(C(=O)O)=C(C)N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 4/20 0.43
HDAC1 Q13547 4/20 0.43
HDAC2 Q92769 4/20 0.43
HDAC8 Q9BY41 4/20 0.43
FFAR3 O14843 3/20 0.43
FNTA P49354 2/20 0.43
FNTB P49356 2/20 0.43
THRB P10828 1/20 0.43
PGGT1B P53609 1/20 0.43
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
CTSD P07339 1/20 0.37
TSHR P16473 3/20 0.36
GRIK1 P39086 2/20 0.35
ALDH1A1 P00352 2/20 0.35
ALOX15 P16050 3/20 0.33
AKR1B1 P15121 1/20 0.33
GRIA4 P48058 1/20 0.33
GRIK3 Q13003 1/20 0.33
GRIK5 Q16478 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12490349 1.00 HDAC3 (0.43) HDAC3HDAC1HDAC2HDAC8FFAR3
Bromide SCHEMBL20239734 0.98 FNTA (0.42) HDAC3HDAC1HDAC2HDAC8FFAR3
Chloromethane SCHEMBL10608041 0.95 FNTA (0.41) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL8325853 0.86 FNTA (0.55) FNTAFNTBTHRBPGGT1BCES2
SCHEMBL8325846 0.86 FNTA (0.55) FNTAFNTBTHRBPGGT1BCES2
SCHEMBL3361436 0.82 CES1 (0.41) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL1557479 0.81 FNTA (0.50) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL184432 0.81 HDAC3 (0.56) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL554603 0.81 HDAC3 (0.56) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL554602 0.81 HDAC3 (0.56) HDAC3HDAC1HDAC2HDAC8FFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1210406-B1 FLOCCULATION OF CELL MATERIAL CIBA SPEC CHEM WATER TREAT LTD (GB) 2010-04-28 EP claimed
WO-2012123966-A1 PROCESS FOR THE PREPARATION OF 4 -SUBSTITUTED -1, 4-DIHYDROPYRIDINES ARCH PHARMALABS LIMITED (IN) 2012-09-20 WO disclosed