SCHEMBL184432

SCHEMBL184432

CCC/C(C(=O)O)=C(\CCC)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 4/20 0.56
HDAC1 Q13547 4/20 0.56
HDAC2 Q92769 4/20 0.56
HDAC8 Q9BY41 4/20 0.56
FFAR3 O14843 3/20 0.56
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
THRB P10828 1/20 0.46
FNTA P49354 1/20 0.46
FNTB P49356 1/20 0.46
PGGT1B P53609 1/20 0.46
TSHR P16473 5/20 0.45
ALDH1A1 P00352 3/20 0.43
AKR1B1 P15121 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
PPARG P37231 6/20 0.39
PPARD Q03181 6/20 0.39
PPARA Q07869 6/20 0.39
GPR84 Q9NQS5 5/20 0.39
HDAC11 Q96DB2 5/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL554602 1.00 HDAC3 (0.56) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL554603 1.00 HDAC3 (0.56) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL305220 0.97 HDAC3 (0.53) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL305222 0.97 HDAC3 (0.53) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL5611368 0.91 FFAR3 (0.48) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL5611361 0.91 FFAR3 (0.48) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL7107841 0.91 FFAR3 (0.48) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL1563512 0.88 HDAC3 (0.50) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL12026335 0.87 FNTA (0.54) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL28284834 0.87 HDAC3 (0.43) HDAC3HDAC1HDAC2HDAC8FFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630661-B2 Additives useful in 3D printing technologies Evonik Operations GmbII (DE) 2026-05-19 US claimed
WO-2023221562-A1 CATALYST SOLID COMPONENT FOR OLEFIN POLYMERIZATION, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 中国科学院化学研究所 2023-11-23 WO claimed
US-20230120872-A1 ADDITIVES USEFUL IN 3D PRINTING TECHNOLOGIES EVONIK OPERATIONS GMBH (DE) 2023-04-20 US claimed
EP-4166332-A1 ADDITIVES USEFUL IN 3D PRINTING TECHNOLOGIES Evonik Operations GmbH (DE) 2023-04-19 EP claimed
US-10870319-B2 Pneumatic tire with post cure sealant layer THE GOODYEAR TIRE & RUBBER COMPANY (US) 2020-12-22 US claimed
EP-1310530-B1 COATING COMPOSITIONS ARKEMA INC (US) 2016-01-06 EP claimed
EP-2373715-A2 OMEGA-FUNCTIONALIZED POLYMERS, JUNCTION-FUNCTIONALIZED BLOCK COPOLYMERS, POLYMER BIOCONJUGATES, AND RADICAL CHAIN EXTENSION POLYMERIZATION University Of Washington (US) 2011-10-12 EP claimed
EP-1812479-B1 MODIFIED CHLORINATED CARBOXYLATED POLYOLEFINS AND THEIR USE AS ADHESION PROMOTERS EASTMAN CHEM CO (US) 2011-10-05 EP claimed
EP-2351801-A1 Aqueous dispersion paints containing lactic acid esters used as film binders Clariant International Ltd. (CH) 2011-08-03 EP claimed
WO-2010077678-A2 OMEGA-FUNCTIONALIZED POLYMERS, JUNCTION-FUNCTIONALIZED BLOCK COPOLYMERS, POLYMER BIOCONJUGATES, AND RADICAL CHAIN EXTENSION POLYMERIZATION UNIVERSITY OF WASHINGTON (US) 2010-07-08 WO claimed
EP-1479737-B1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC (US) 2006-08-16 EP claimed
EP-1608689-A1 REMOVAL OF THIOCARBONYL END GROUPS OF POLYMERS Symyx Technologies, Inc. (US) 2005-12-28 EP claimed
EP-1423441-B1 MODIFIED CARBOXYLATED POLYOLEFINS AND THEIR USE AS ADHESION PROMOTERS EASTMAN CHEM CO (US) 2005-11-09 EP claimed
US-6919409-B2 Removal of the thiocarbonylthio or thiophosphorylthio end group of polymers and further functionalization thereof SYMYX TECHNOLOGIES, INC. (US) 2005-07-19 US claimed
US-20040266953-A1 Removal of the thiocarbonylthio or thiophosphorylthio end group of polymers and further functionalization thereof SYMYX TECHNOLOGIES, INC. 2004-12-30 US claimed
WO-2004089994-A1 REMOVAL OF THIOCARBONYL END GROUPS OF POLYMERS SYMYX TECHNOLOGIES, INC. (US) 2004-10-21 WO claimed
EP-1366087-B1 UV-CURABLE, NON-CHLORINATED ADHESION PROMOTERS EASTMAN CHEM CO (US) 2004-08-11 EP claimed
EP-1208135-B1 IN-SITU PREPARATION OF POLYASPARTIC ESTER MIXTURE BAYER AG (US) 2003-10-01 EP claimed
EP-1044224-B1 POLYOLEFINS FUNCTIONALIZED WITH MALEIC ANHYDRIDE AND WITH ITS HIGH-BOILING LIQUID ESTERS, AND THEIR USE AS PRODUCTS WITH HIGH COMPATIBILIZING POWER BELANTRO INTERNAT CORP (PA) 2003-06-25 EP claimed
EP-1059328-A1 One-component polyurethane foam compositions with improved curing behaviour HILTI Aktiengesellschaft (LI) 2000-12-13 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630661-B2 Additives useful in 3D printing technologies HTR3D, HTR3B, HTR3C HDAC3 2594/4885HDAC1 3511/4885HDAC2 2343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.