SCHEMBL31338486

SCHEMBL31338486

CCOC(=O)c1cnc(SC)nc1C(C)=O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.63
KMT2A Q03164 2/20 0.63
ALDH1A1 P00352 6/20 0.58
TDP1 Q9NUW8 2/20 0.58
POLB P06746 1/20 0.58
SYK P43405 2/20 0.55
MAPT P10636 5/20 0.54
HPGD P15428 2/20 0.54
KDM4E B2RXH2 1/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
NFKB1 P19838 2/20 0.52
NFKB2 Q00653 2/20 0.52
RELA Q04206 2/20 0.52
LMNA P02545 1/20 0.52
FOS P01100 1/20 0.52
JUN P05412 1/20 0.52
MAPK1 P28482 2/20 0.51
HTT P42858 1/20 0.51
RAB9A P51151 3/20 0.48
NPC1 O15118 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14633377 1.00 MEN1 (0.63) MEN1KMT2AALDH1A1TDP1POLB
SCHEMBL5768489 0.91 MEN1 (0.66) MEN1KMT2AALDH1A1TDP1POLB
SCHEMBL20649220 0.89 MEN1 (0.63) MEN1KMT2AALDH1A1TDP1POLB
SCHEMBL31338477 0.86 MEN1 (0.60) MEN1KMT2AALDH1A1TDP1POLB
SCHEMBL14633589 0.86 MEN1 (0.60) MEN1KMT2AALDH1A1TDP1POLB
SCHEMBL14632941 0.85 MEN1 (0.57) MEN1KMT2AALDH1A1TDP1POLB
SCHEMBL14632979 0.85 MEN1 (0.59) MEN1KMT2AALDH1A1TDP1POLB
SCHEMBL5808541 0.84 MEN1 (0.58) MEN1KMT2AALDH1A1TDP1POLB
SCHEMBL423187 0.84 MEN1 (0.64) MEN1KMT2AALDH1A1TDP1POLB
SCHEMBL29897636 0.84 MEN1 (0.64) MEN1KMT2AALDH1A1TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119343346-A Benzenesulfonamide derivative, process for preparing the same, and pharmaceutical composition for preventing or treating cancer containing the same as active ingredient 韩国化学研究院 2025-01-21 CN disclosed