Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SYK | P43405 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | FOS | P01100 | 1/20 | 0.48 |
| ▸ | JUN | P05412 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL188686 | 0.93 | MAPT (0.61) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL29506595 | 0.93 | MAPT (0.61) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL5768489 | 0.92 | MEN1 (0.66) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL31338486 | 0.84 | MEN1 (0.63) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL14633377 | 0.84 | MEN1 (0.63) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL20649220 | 0.84 | MEN1 (0.63) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL18673593 | 0.83 | MAPT (0.51) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL31338477 | 0.82 | MEN1 (0.60) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL14633589 | 0.82 | MEN1 (0.60) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL7017546 | 0.81 | ALDH1A1 (0.54) | MEN1KMT2AMAPTHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1625130-A2 | HIV INTEGRASE INHIBITORS | Tibotec Pharmaceuticals Ltd. (IE) | 2006-02-15 | — | — | EP | disclosed |
| WO-2004096807-A2 | HIV INTEGRASE INHIBITORS | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2004-11-11 | — | — | WO | disclosed |