Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | P4HB | P07237 | 7/20 | 0.53 |
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL99552 | 1.00 | MAPT (0.61) | MAPTHTTALDH1A1GAAHPGD | |
| SCHEMBL30440633 | 1.00 | MAPT (0.61) | MAPTHTTALDH1A1GAAHPGD | |
| SCHEMBL99553 | 1.00 | MAPT (0.61) | MAPTHTTALDH1A1GAAHPGD | |
| SCHEMBL8837777 | 0.86 | ALDH1A1 (0.47) | MAPTHTTALDH1A1GAAHPGD | |
| Dimethylformamide SCHEMBL8837774 | 0.84 | MAPT (0.45) | MAPTHTTALDH1A1GAAHPGD | |
| SCHEMBL5946453 | 0.84 | MAPT (0.77) | MAPTHTTALDH1A1GAAHPGD | |
| SCHEMBL1873928 | 0.82 | NR1H3 (0.51) | MAPTHTTALDH1A1GAAHPGD | |
| SCHEMBL1873930 | 0.82 | NR1H3 (0.51) | MAPTHTTALDH1A1GAAHPGD | |
| SCHEMBL2162706 | 0.81 | MAPT (0.62) | MAPTHTTALDH1A1GAAHPGD | |
| SCHEMBL2162703 | 0.81 | MAPT (0.62) | MAPTHTTALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119031913-A | Purine and methods of use thereof | 奇尼塔公司 | 2024-11-26 | — | — | CN | disclosed |