Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31339611 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2TSHRL3MBTL1LMNATDP1 | |
| SCHEMBL31339594 | 0.88 | SMN1; SMN2 (0.46) | SMN1; SMN2TSHRL3MBTL1LMNATDP1 | |
| SCHEMBL31339563 | 0.86 | SLC6A3 (0.50) | SMN1; SMN2TSHRL3MBTL1LMNATDP1 | |
| SCHEMBL1640291 | 0.82 | CA12 (0.41) | SMN1; SMN2TSHRL3MBTL1LMNABRD4 | |
| SCHEMBL31339585 | 0.80 | SMN1; SMN2 (0.39) | SMN1; SMN2TSHRL3MBTL1LMNATDP1 | |
| SCHEMBL31339591 | 0.79 | CA12 (0.44) | SMN1; SMN2TSHRL3MBTL1LMNATDP1 | |
| SCHEMBL1641959 | 0.79 | KDM4E (0.48) | SMN1; SMN2TSHRLMNABRD4MAPT | |
| SCHEMBL30910244 | 0.75 | CNR1 (0.49) | TDP1BRD4GAANR4A2CNR1 | |
| SCHEMBL17156651 | 0.74 | BAZ2B (0.47) | TSHRL3MBTL1LMNAGAAMAPT | |
| SCHEMBL1642110 | 0.72 | HSP90AA1 (0.48) | SMN1; SMN2LMNABRD4MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119384422-A | Pyridazinopyridone derivatives and uses thereof | 四川汇宇制药股份有限公司 | 2025-01-28 | — | — | CN | disclosed |