SCHEMBL31340098

SCHEMBL31340098

Brc1c(Br)c(Br)c2c(ccc3c4ccccc4ccc32)c1Br

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HPRT1 P00492 4/20 0.58
▸ HSD17B10 Q99714 4/20 0.50
▸ ALDH1A1 P00352 4/20 0.50
▸ TSHR P16473 2/20 0.50
▸ TDP1 Q9NUW8 2/20 0.50
▸ CYP2A6 P11509 1/20 0.50
▸ CYP1A2 P05177 3/20 0.48
▸ HPGD P15428 3/20 0.48
▸ THRB P10828 1/20 0.48
▸ POLB P06746 1/20 0.45
▸ ERBB2 P04626 1/20 0.44
▸ FYN P06241 1/20 0.44
▸ MAOA P21397 1/20 0.44
▸ ACHE P22303 1/20 0.44
▸ AHR P35869 1/20 0.44
▸ PAX8 Q06710 1/20 0.43
▸ HIF1A Q16665 3/20 0.43
▸ CYP1B1 Q16678 1/20 0.43
▸ MAPK1 P28482 3/20 0.40
▸ CYP3A4 P08684 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11197647 0.91 HPRT1 (0.50) HPRT1HSD17B10ALDH1A1TSHRTDP1
SCHEMBL1377289 0.83 HPRT1 (0.50) HPRT1HSD17B10ALDH1A1TSHRTDP1
SCHEMBL3701854 0.79 HPRT1 (0.82) HPRT1HSD17B10ALDH1A1TSHRTDP1
SCHEMBL4855632 0.79 HPRT1 (0.82) HPRT1HSD17B10ALDH1A1TSHRTDP1
SCHEMBL69097 0.79 HPRT1 (0.82) HPRT1HSD17B10ALDH1A1TSHRTDP1
SCHEMBL2848750 0.78 HPRT1 (0.50) HPRT1HSD17B10ALDH1A1TSHRTDP1
SCHEMBL2679230 0.78 HPRT1 (0.56) HPRT1HSD17B10ALDH1A1TSHRTDP1
SCHEMBL4851786 0.77 HPRT1 (0.78) HPRT1HSD17B10ALDH1A1TSHRTDP1
SCHEMBL4846677 0.77 HPRT1 (0.78) HPRT1HSD17B10ALDH1A1TSHRTDP1
SCHEMBL4853390 0.77 HPRT1 (0.78) HPRT1HSD17B10ALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260042726-A1 ENCODED DESIGN INTEGRATED SYNTHESIS OF NUCLEIC ACIDS, AND PHOSPHOLIPIDS, AND RELATED PHARMACEUTICAL PRODUCTS SCHAPER CHARLES (US) 2026-02-12 — — US disclosed
US-12473247-B2 Encoded design integrated synthesis of nucleic acids, and phospholipids, and related pharmaceutical products Schaper, Charles (US) 2025-11-18 — — US disclosed
US-20250074853-A1 ENCODED DESIGN INTEGRATED SYNTHESIS OF NUCLEIC ACIDS, AND PHOSPHOLIPIDS, AND RELATED PHARMACEUTICAL PRODUCTS SCHAPER CHARLES (US) 2025-03-06 — — US disclosed
US-12195423-B1 Encoded design integrated synthesis of nucleic acids, and phospholipids, and related pharmaceutical products SCHAPER CHARLES (US) 2025-01-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12195423-B1 Encoded design integrated synthesis of nucleic acids, and phospholipids, and related pharmaceutical products POLRMT, TARBP1, PHOSPHO1 HPRT1 478/4885HSD17B10 1926/4885ALDH1A1 4705/4885
US-20250074853-A1 ENCODED DESIGN INTEGRATED SYNTHESIS OF NUCLEIC ACIDS, AND PHOSPHOLIPIDS, AND RELATED PHARMACEUTICAL PRODUCTS POLRMT, TARBP1, PHOSPHO1 HPRT1 478/4885HSD17B10 1926/4885ALDH1A1 4705/4885
US-12473247-B2 Encoded design integrated synthesis of nucleic acids, and phospholipids, and related pharmaceutical products POLRMT, TARBP1, PHOSPHO1 HPRT1 478/4885HSD17B10 1926/4885ALDH1A1 4705/4885
US-20260042726-A1 ENCODED DESIGN INTEGRATED SYNTHESIS OF NUCLEIC ACIDS, AND PHOSPHOLIPIDS, AND RELATED PHARMACEUTICAL PRODUCTS POLRMT, POLM, PHOSPHO1 HPRT1 1907/4885HSD17B10 2189/4885ALDH1A1 3743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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