Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11343825 | 0.88 | TSHR (0.33) | TSHRSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL320574 | 0.87 | TSHR (0.46) | TSHRSLC6A2SLC6A3SLC6A4MAOB | |
| SCHEMBL28469171 | 0.85 | TSHR (0.45) | TSHRSLC6A2SLC6A3SLC6A4MAOB | |
| SCHEMBL29844948 | 0.85 | TSHR (0.45) | TSHRSLC6A2SLC6A3SLC6A4SLC18A3 | |
| SCHEMBL29503026 | 0.85 | TSHR (0.45) | TSHRSLC6A2SLC6A3SLC6A4MAOB | |
| Hydrochloric Acid SCHEMBL28154421 | 0.84 | TSHR (0.43) | TSHRSLC6A2SLC6A3SLC6A4SMN1; SMN2 | |
| Hexane SCHEMBL28169137 | 0.77 | TSHR (0.37) | TSHRSLC6A2SLC6A3SLC6A4ALDH1A1 | |
| SCHEMBL27903480 | 0.77 | CYP2A6 (0.51) | ALDH1A1CYP2C19MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5162162 | 0.73 | TSHR (0.64) | TSHRSLC6A2SLC6A3SLC6A4MAOB | |
| SCHEMBL1195857 | 0.73 | TSHR (0.64) | TSHRSLC6A2SLC6A3SLC6A4MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10669250-B2 | Hypervalent iodine CF2CF2X reagents and their use | ETH ZURICH (CH) | 2020-06-02 | — | — | US | claimed |
| US-20190040036-A1 | HYPERVALENT IODINE CF2CF2X REAGENTS AND THEIR USE | ETH ZURICH (CH) | 2019-02-07 | — | — | US | claimed |
| EP-0370454-B1 | Renin-inhibiting amino diol derivatives | HOECHST AG (DE) | 1994-04-20 | — | — | EP | claimed |
| EP-0370454-A2 | Renin-inhibiting amino diol derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-30 | — | — | EP | claimed |
| CN-116462654-B | Preparation method of cyclic ethylene carbonate compound | 上海如鲲新材料股份有限公司 | 2025-06-10 | — | — | CN | disclosed |
| CN-116462654-A | Preparation method of cyclic ethylene carbonate compound | 上海如鲲新材料股份有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-114981270-A | MLL1 inhibitors and anticancer agents | 诺华公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-114929705-A | MLL1 inhibitor and anticancer agent | 诺华公司 | 2022-08-19 | — | — | CN | disclosed |
| US-10669250-B2 | Hypervalent iodine CF2CF2X reagents and their use | ETH ZURICH (CH) | 2020-06-02 | — | — | US | disclosed |
| US-20190040036-A1 | HYPERVALENT IODINE CF2CF2X REAGENTS AND THEIR USE | ETH ZURICH (CH) | 2019-02-07 | — | — | US | disclosed |
| CN-108699106-A | Novel trifluoromethyl propanamide derivative as HTRA1 inhibitor | 豪夫迈·罗氏有限公司 | 2018-10-23 | — | — | CN | disclosed |
| US-8754175-B2 | Monocapped conductive polymers with alkenyl or alkynyl end groups and block copolymers therefrom | CARNEGIE MELLON UNIVERSITY (US) | 2014-06-17 | — | — | US | disclosed |
| US-5317050-A | Hydrolyzable aryl pohosphite for hardening phenolic resins, furfuryl alcohol accelerater | BORDEN, INC. (US) | 1994-05-31 | — | — | US | disclosed |
| EP-0370454-B1 | Renin-inhibiting amino diol derivatives | HOECHST AG (DE) | 1994-04-20 | — | — | EP | disclosed |
| EP-0589039-A1 | TRIPHENYLETHYLENE DERIVATIVE AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1994-03-30 | — | — | EP | disclosed |
| US-5296520-A | Phenolic resin with aryl phosphite, increasing acidity and hydrolysis of phosphite | BORDEN, INC. (US) | 1994-03-22 | — | — | US | disclosed |
| US-5272140-A | 11-aryl steroid derivatives | AKZO N.V. (NL) | 1993-12-21 | — | — | US | disclosed |
| EP-0277676-B1 | NEW LL-ARYL STEROID DERIVATIVES | AKZO N.V. (NL) | 1992-03-04 | — | — | EP | disclosed |
| EP-0370454-A2 | Renin-inhibiting amino diol derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-30 | — | — | EP | disclosed |
| EP-0277676-A1 | New ll-aryl steroid derivatives | AKZO N.V. (NL) | 1988-08-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10669250-B2 | Hypervalent iodine CF2CF2X reagents and their use | TPO, FANCF, FANCI | TSHR 14/4885SLC6A2 1529/4885SLC6A3 632/4885 |
| US-20190040036-A1 | HYPERVALENT IODINE CF2CF2X REAGENTS AND THEIR USE | TPO, FANCF, FANCI | TSHR 14/4885SLC6A2 1529/4885SLC6A3 632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.