Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CPB1 | P15086 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6347796 | 0.93 | CPB1 (0.49) | PDE4BSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL16164661 | 0.87 | PDE4B (0.56) | PDE4BSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL14911483 | 0.87 | PDE4B (0.56) | PDE4BSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL16096196 | 0.87 | PDE4B (0.57) | PDE4BSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL13707624 | 0.86 | PDE4B (0.56) | PDE4BSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL16841203 | 0.86 | PDE4B (0.56) | PDE4BSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL18258160 | 0.86 | PDE4B (0.53) | PDE4BSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL18247458 | 0.86 | PDE4B (0.53) | PDE4BSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL21335664 | 0.86 | PDE4B (0.53) | PDE4BSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL376543 | 0.86 | PDE4B (0.53) | PDE4BSMN1; SMN2NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747250-A1 | KINASE INHIBITORS | The United States Of America, As Represented By The Secretary, Department of Health and Human Services (US) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025019585-A1 | KINASE INHIBITORS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2025-01-23 | — | — | WO | disclosed |