Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 2/20 | 0.39 |
| ▸ | SYK | P43405 | 13/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.35 |
| ▸ | MERTK | Q12866 | 2/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10050287 | 0.88 | KMT2A (0.50) | KMT2AAXLSYKTYRO3MERTK | |
| SCHEMBL31612124 | 0.88 | KMT2A (0.50) | KMT2AAXLSYKTYRO3MERTK | |
| SCHEMBL762040 | 0.85 | KMT2A (0.55) | KMT2AAXLSYKMAPK8 | |
| SCHEMBL31612129 | 0.85 | KMT2A (0.55) | KMT2AAXLSYKMAPK8 | |
| SCHEMBL13518145 | 0.85 | KMT2A (0.58) | KMT2AAXLSYKTYRO3MERTK | |
| Fluoride SCHEMBL13518132 | 0.84 | KMT2A (0.57) | KMT2AAXLSYKTYRO3MERTK | |
| SCHEMBL20299364 | 0.84 | KMT2A (0.61) | KMT2AAXLSYKTYRO3MERTK | |
| SCHEMBL14981603 | 0.84 | KMT2A (0.42) | KMT2AAXLSYKTYRO3MERTK | |
| SCHEMBL31340871 | 0.83 | NR2F2 (0.51) | KMT2ASYK | |
| SCHEMBL23452652 | 0.83 | MAPK8 (0.48) | KMT2AAXLSYKTYRO3MERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049247-A1 | 5,6-CORE SILACYCLE BASED INHIBITORS OF DNA-DEPENDENT PROTEIN KINASE AND COMPOSITIONS AND APPLICATION IN GENE EDITING | JUNO THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |