SCHEMBL31341919

SCHEMBL31341919

COc1ccc(CN2C(=O)CCC(n3c(=O)n(C)c4c(N5CCC(c6ccc(Cl)cc6)CC5)cccc43)C2=O)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.40
▸ KMT2A Q03164 3/20 0.40
▸ LMNA P02545 1/20 0.40
▸ ADRA1D P25100 4/20 0.39
▸ ADRA1A P35348 4/20 0.39
▸ ADRA1B P35368 4/20 0.39
▸ DGAT1 O75907 1/20 0.37
▸ GSK3B P49841 1/20 0.37
▸ TP53 P04637 1/20 0.37
▸ THRB P10828 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ ALDH1A1 P00352 4/20 0.36
▸ MAPT P10636 1/20 0.36
▸ HCRTR1 O43613 2/20 0.36
▸ HCRTR2 O43614 2/20 0.36
▸ TSHR P16473 1/20 0.36
▸ DRD2 P14416 2/20 0.36
▸ DRD4 P21917 2/20 0.35
▸ SCN9A Q15858 1/20 0.35
▸ NR3C1 P04150 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31342545 0.88 MEN1 (0.36) MEN1KMT2ALMNADGAT1TP53
SCHEMBL27224929 0.86 MEN1 (0.41) MEN1KMT2ALMNAGSK3BTP53
SCHEMBL27225261 0.86 MEN1 (0.41) MEN1KMT2ALMNAGSK3BTP53
SCHEMBL27225016 0.86 MEN1 (0.42) MEN1KMT2ALMNAGSK3BTP53
SCHEMBL27225524 0.86 MEN1 (0.41) MEN1KMT2ALMNAGSK3BTP53
SCHEMBL29179828 0.85 MEN1 (0.40) MEN1KMT2ALMNAGSK3BTP53
SCHEMBL31342256 0.83 MEN1 (0.40) MEN1KMT2ALMNAADRA1BGSK3B
SCHEMBL31727473 0.83 MEN1 (0.40) MEN1KMT2ALMNAADRA1BGSK3B
SCHEMBL27225054 0.82 MEN1 (0.38) MEN1KMT2ALMNAGSK3BALDH1A1
SCHEMBL31342077 0.82 MEN1 (0.39) MEN1KMT2ALMNAADRA1BGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124309-A1 STAT6 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-05-07 — — US disclosed
WO-2025049820-A1 STAT6 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. (US) 2025-03-06 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260124309-A1 STAT6 DEGRADERS AND USES THEREOF STAT6, NCOR2, NCOR1 MEN1 4497/4885KMT2A 1231/4885LMNA 4019/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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