Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27225261 | 0.94 | MEN1 (0.41) | MEN1KMT2ALMNAHCRTR1HCRTR2 | |
| SCHEMBL27225054 | 0.88 | MEN1 (0.38) | MEN1KMT2ALMNAHCRTR1HCRTR2 | |
| SCHEMBL27224929 | 0.87 | MEN1 (0.41) | MEN1KMT2ALMNAHCRTR1HCRTR2 | |
| SCHEMBL27225016 | 0.87 | MEN1 (0.42) | MEN1KMT2ALMNAHCRTR1HCRTR2 | |
| SCHEMBL31129691 | 0.87 | BACE1 (0.39) | MEN1KMT2ALMNAALDH1A1TP53 | |
| SCHEMBL25583861 | 0.86 | MEN1 (0.37) | MEN1KMT2ALMNAHCRTR1HCRTR2 | |
| SCHEMBL29179829 | 0.86 | ACHE (0.36) | MEN1KMT2ALMNAHCRTR1HCRTR2 | |
| SCHEMBL27225524 | 0.86 | MEN1 (0.41) | MEN1KMT2ALMNAHCRTR1HCRTR2 | |
| SCHEMBL25122941 | 0.86 | MEN1 (0.36) | MEN1KMT2ALMNAHCRTR1HCRTR2 | |
| SCHEMBL22836063 | 0.85 | LMNA (0.41) | MEN1KMT2ALMNAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794936-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2024-03-29 | — | — | CN | disclosed |