Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | TNF | P01375 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 7/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21326445 | 0.87 | KDM4E (0.44) | PIK3CAPIK3CBPIK3CGPI4KBHDAC1 | |
| SCHEMBL29644660 | 0.85 | ALDH1A1 (0.45) | PIK3CAPIK3CBPIK3CGPI4KBHDAC1 | |
| SCHEMBL9955853 | 0.85 | ALDH1A1 (0.45) | PIK3CAPIK3CBPIK3CGPI4KBHDAC1 | |
| SCHEMBL11589979 | 0.84 | ALDH1A1 (0.54) | PIK3CAPIK3CBPIK3CGPI4KBHDAC1 | |
| SCHEMBL9957845 | 0.84 | PIK3CA (0.44) | PIK3CAPIK3CBPIK3CGPI4KBHDAC1 | |
| SCHEMBL2275524 | 0.82 | SMN1; SMN2 (0.55) | PIK3CAPIK3CBPIK3CGPI4KBHDAC1 | |
| SCHEMBL20031462 | 0.82 | ALDH1A1 (0.46) | PIK3CAPIK3CBPIK3CGPI4KBHDAC1 | |
| SCHEMBL31342152 | 0.81 | TTR (0.44) | KDM4EALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL21195563 | 0.81 | NPC1 (0.42) | PIK3CAPIK3CBPIK3CGPI4KBHDAC1 | |
| SCHEMBL23730805 | 0.80 | NPC1 (0.44) | PIK3CAPIK3CBPIK3CGPI4KBHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260124309-A1 | STAT6 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS INC (US) | 2026-05-07 | — | — | US | disclosed |
| WO-2025049820-A1 | STAT6 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260124309-A1 | STAT6 DEGRADERS AND USES THEREOF | STAT6, NCOR2, NCOR1 | PIK3CA 2634/4885PIK3CB 2553/4885PIK3CG 3049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.