SCHEMBL31342136

SCHEMBL31342136

Fc1c(Cl)ccc(Br)c1F

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.39
KCNH2 Q12809 2/20 0.39
KDM1B Q8NB78 2/20 0.39
USP2 O75604 1/20 0.34
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2014602 1.00 KDM1A (0.39) KDM1AKCNH2KDM1BUSP2HPGD
SCHEMBL20918502 0.82 USP2 (0.41) USP2HPGD
SCHEMBL29638160 0.82 USP2 (0.41) USP2HPGD
SCHEMBL29666934 0.82 KDM1A (0.48) KDM1AKCNH2KDM1B
SCHEMBL855230 0.82 KDM1A (0.48) KDM1AKCNH2KDM1B
SCHEMBL2013956 0.81 CYP3A4 (0.35) KDM1AKCNH2KDM1B
SCHEMBL30223191 0.81 HTR2A (0.32)
SCHEMBL31070219 0.81 CYP3A4 (0.35) KDM1AKCNH2KDM1B
SCHEMBL23403883 0.77 NOTUM (0.30)
SCHEMBL1224150 0.77 CDC7 (0.36) KDM1AKCNH2KDM1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025049820-A1 STAT6 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. (US) 2025-03-06 WO disclosed