SCHEMBL855230

SCHEMBL855230

Fc1c(Br)ccc(Br)c1F

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 4/20 0.48
KCNH2 Q12809 4/20 0.48
KDM1B Q8NB78 3/20 0.48
CYP2A6 P11509 1/20 0.33
HSP90AA1 P07900 1/20 0.30
TLR9 Q9NR96 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29666934 1.00 KDM1A (0.48) KDM1AKCNH2KDM1BCYP2A6HSP90AA1
SCHEMBL29544666 0.87 KDM1A (0.41) KDM1AKCNH2KDM1B
SCHEMBL577838 0.87 KDM1A (0.41) KDM1AKCNH2KDM1B
SCHEMBL21617924 0.82 KDM1A (0.38) KDM1AKCNH2KDM1B
SCHEMBL2487490 0.82 KDM1A (0.39) KDM1AKCNH2KDM1B
SCHEMBL441345 0.82 KDM1A (0.43) KDM1AKCNH2KDM1B
SCHEMBL2014602 0.82 KDM1A (0.39) KDM1AKCNH2KDM1B
SCHEMBL10301570 0.82 KDM1A (0.39) KDM1AKCNH2KDM1B
SCHEMBL258026 0.82 ALOX15 (0.40) KDM1AKCNH2KDM1B
SCHEMBL31342136 0.82 KDM1A (0.39) KDM1AKCNH2KDM1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924237-A ((2, 3-Diamino-5, 6-difluoro-1, 4-phenyl) bis (thiophene-5, 2-diyl)) bis (2-cyanoacrylate) and preparation method and application thereof 湘潭大学 2024-04-26 CN claimed
CN-113042011-B Application of fluorine-containing conjugated microporous polymer 南昌航空大学 2022-07-12 CN claimed
CN-113683601-A Diaza-benzo-fluoranthene compound and preparation method and application thereof 广东工业大学 2021-11-23 CN claimed
CN-113042011-A Fluorine-containing conjugated microporous polymer and preparation method and application thereof 南昌航空大学 2021-06-29 CN claimed
US-20260124309-A1 STAT6 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-05-07 US disclosed
US-12617798-B2 Imidazopyrazne derivatives HOFFMANN-LA ROCHE INC. (US) 2026-05-05 US disclosed
US-12600698-B2 Kinase inhibitors VIDYA THERAPEUTICS, INC. (US) 2026-04-14 US disclosed
EP-4698516-A1 PYRROLIDINONE UREA FPR2 AGONISTS Bristol-Myers Squibb Company (US) 2026-02-25 EP disclosed
EP-4698275-A1 PYRROLIDINONE UREA FPR2 AGONISTS Bristol-Myers Squibb Company (US) 2026-02-25 EP disclosed
US-12559486-B2 Tau-protein targeting compounds and associated methods of use ARVINAS OPERATIONS, INC. (US) 2026-02-24 US disclosed
EP-3941919-B1 PYRIDO-PYRIMIDINONE AND PTERIDINONE COMPOUNDS AS INHIBITORS OF ENDORIBONUCLEASE INOSITOL REQUIRING ENZYME I (IRE I ALPHA) FOR THE TREATMENT OF CANCER DISEASES. GENENTECH INC (US) 2025-12-24 EP disclosed
US-20250353862-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-11-20 US disclosed
US-6433231-B2 BROMINATION THE CORRESPONDING NAPHTHALENE HALOGEN COMPOUND NIPPON SHOKUBAI CO., LTD. (JP) 2002-08-13 US disclosed
US-20010045350-A1 Method for production of halogen-containing aromatic compound NIPPON SHOKUBAI CO., LTD., A JAPAN CORPORATION 2001-11-29 US disclosed
JP-2001247501-A AROMATIC COMPOUND AND METHOD OF PRODUCING THE SAME NIPPON SHOKUBAI CO LTD 2001-09-11 JP disclosed
US-6288290-B1 BROMINATION AND PHOTOBROMINATION OF AROMATIC COMPOUNDS NIPPON SHOKUBAI, CO., LTD. (JP) 2001-09-11 US disclosed
EP-0995734-A1 Method for production of halogen-containing aromatic compound Nippon Shokubai Co., Ltd. (JP) 2000-04-26 EP disclosed
EP-0578054-B1 Meta-substituted six membered aromatic rings for use in liquid crystal mixtures HOECHST AG (DE) 1999-05-19 EP disclosed
US-5447656-A Meta-substituted aromatic compounds having six-membered rings, for use in liquid-crystal mixtures HOECHST AKTIENGESELLSCHAFT (DE) 1995-09-05 US disclosed
EP-0578054-A1 Meta-substituted six membered aromatic rings for use in liquid crystal mixtures HOECHST AKTIENGESELLSCHAFT (DE) 1994-01-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260124309-A1 STAT6 DEGRADERS AND USES THEREOF STAT6, NCOR2, NCOR1 KDM1A 1642/4885KCNH2 4066/4885KDM1B 982/4885
US-12600698-B2 Kinase inhibitors BTK, BMX, GSK3B KDM1A 2098/4885KCNH2 1794/4885KDM1B 2642/4885
US-20010045350-A1 Method for production of halogen-containing aromatic compound CBR1, CBR3, DCXR KDM1A 1663/4885KCNH2 20/4885KDM1B 1115/4885
US-20250353862-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 KDM1A 3210/4885KCNH2 4582/4885KDM1B 2718/4885
US-12617798-B2 Imidazopyrazne derivatives CLIC1, HCFC1, CXCR1 KDM1A 1299/4885KCNH2 113/4885KDM1B 2226/4885
US-12559486-B2 Tau-protein targeting compounds and associated methods of use UBQLN2, UBQLN1, CRBN KDM1A 470/4885KCNH2 4049/4885KDM1B 381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.