Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 8/20 | 0.62 |
| ▸ | QDPR | P09417 | 1/20 | 0.53 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.52 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | STS | P08842 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PDE4A | P27815 | 2/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21404026 | 1.00 | PDE4B (0.62) | PDE4BQDPRADAM17ADAMTS5NAMPT | |
| SCHEMBL4735264 | 0.88 | NAMPT (0.54) | PDE4BNAMPTMEN1KMT2ASTS | |
| SCHEMBL31342129 | 0.87 | PDE4B (0.51) | PDE4BQDPRNAMPTMEN1KMT2A | |
| SCHEMBL19703066 | 0.86 | PDE4B (0.56) | PDE4BQDPRADAM17ADAMTS5NAMPT | |
| SCHEMBL19702756 | 0.86 | PDE4B (0.62) | PDE4BQDPRNAMPTMEN1KMT2A | |
| SCHEMBL310046 | 0.86 | PDE4B (0.62) | PDE4BQDPRNAMPTMEN1KMT2A | |
| SCHEMBL30957975 | 0.86 | PDE4B (0.62) | PDE4BQDPRNAMPTMEN1KMT2A | |
| SCHEMBL19701838 | 0.86 | PDE4B (0.53) | PDE4BQDPRADAM17ADAMTS5NAMPT | |
| SCHEMBL19703149 | 0.85 | NAMPT (0.52) | PDE4BNAMPTMEN1KMT2ASTS | |
| SCHEMBL18310125 | 0.85 | PDE4B (0.61) | PDE4BQDPRNAMPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260124309-A1 | STAT6 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS INC (US) | 2026-05-07 | — | — | US | disclosed |
| WO-2025049820-A1 | STAT6 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260124309-A1 | STAT6 DEGRADERS AND USES THEREOF | STAT6, NCOR2, NCOR1 | PDE4B 4018/4885QDPR 1071/4885ADAM17 4737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.