SCHEMBL3134285

SCHEMBL3134285

CCOC(=O)C(N)CCNS(=O)(=O)c1nc2cc(Cl)ccc2s1

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 14/20 0.44
CA9 Q16790 1/20 0.43
F10 P00742 1/20 0.42
ALOX5 P09917 1/20 0.41
PTPN1 P18031 1/20 0.40
CA2 P00918 2/20 0.40
CA1 P00915 1/20 0.40
LMNA P02545 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3136533 0.82 CA2 (0.42) PPARACA9F10ALOX5PTPN1
SCHEMBL7062250 0.78 PPARA (0.46) PPARACA9ALOX5PTPN1CA2
SCHEMBL3614648 0.71 SMN1; SMN2 (0.53) PPARAALOX5PTPN1LMNASMN1; SMN2
SCHEMBL3124867 0.70 MAPK1 (0.47) CA2CA1SMN1; SMN2
SCHEMBL3124873 0.70 MAPK1 (0.47) CA2CA1SMN1; SMN2
SCHEMBL3139946 0.70 PPARA (0.39) PPARAF10ALOX5CA2CA1
SCHEMBL16595635 0.69 PTPN1 (0.52) PPARAALOX5PTPN1LMNASMN1; SMN2
SCHEMBL5946353 0.69 PPARA (0.73) PPARAALOX5SMN1; SMN2
SCHEMBL1748164 0.67 SMN1; SMN2 (0.53) PPARAALOX5CA2SMN1; SMN2
SCHEMBL9439505 0.67 SMN1; SMN2 (0.42) PPARACA9ALOX5CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2174936-B1 PNA monomer and precursor PANAGENE INC (KR) 2013-09-04 EP disclosed
EP-2174936-A1 PNA monomer and precursor Panagene, Inc. (KR) 2010-04-14 EP disclosed
EP-1501812-B1 PNA MONOMER AND PRECURSOR PANAGENE INC (KR) 2009-12-30 EP disclosed
CN-100347161-C PNA monomer and precursor PANAGENE INC (KR) 2007-11-07 CN disclosed
EP-1501812-A4 PNA MONOMER AND PRECURSOR PANAGENE INC (KR) 2006-05-24 EP disclosed
CN-1659153-A PNA monomer and precursor PANAGENE INC (KR) 2005-08-24 CN disclosed
EP-1501812-A1 PNA MONOMER AND PRECURSOR Panagene, Inc. (KR) 2005-02-02 EP disclosed
WO-2003091231-A1 PNA MONOMER AND PRECURSOR PANAGENE, INC. (US) 2003-11-06 WO disclosed