Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 11/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | TIPARP | Q7Z3E1 | 5/20 | 0.37 |
| ▸ | LCAT | P04180 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31342795 | 0.91 | CYP3A4 (0.53) | CYP3A4CYP2C9CYP2C19GPR119 | |
| SCHEMBL31342844 | 0.90 | CYP3A4 (0.44) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31342842 | 0.84 | CYP3A4 (0.40) | CYP3A4CYP2C9CYP2C19GPR119TIPARP | |
| SCHEMBL31342843 | 0.81 | CYP3A4 (0.52) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31342879 | 0.81 | CYP3A4 (0.43) | CYP3A4CYP2C9CYP2C19GPR119 | |
| SCHEMBL31342957 | 0.80 | CYP3A4 (0.65) | CYP3A4CYP2C9CYP2C19GPR119 | |
| SCHEMBL31343043 | 0.80 | CYP3A4 (0.52) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31342875 | 0.79 | CYP3A4 (0.40) | CYP3A4 | |
| SCHEMBL31343083 | 0.78 | CYP3A4 (0.46) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31342857 | 0.77 | CYP3A4 (0.46) | CYP3A4GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049495-A1 | TERTIARY PYRIDYL AMINE MODULATORS OF CHOLESTEROL BIOSYNTHESIS AND THEIR USE FOR PROMOTING REMYLINATION | GENENTECH, INC. (US) | 2025-03-06 | — | — | WO | disclosed |