Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 9/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31342964 | 0.88 | CYP3A4 (0.40) | CYP3A4GPBAR1PIK3CAKCNH2APP | |
| SCHEMBL31343027 | 0.87 | CYP3A4 (0.42) | CYP3A4GPBAR1 | |
| Hydrochloric Acid SCHEMBL31342860 | 0.86 | CYP3A4 (0.42) | CYP3A4GPBAR1 | |
| SCHEMBL31343035 | 0.83 | CYP3A4 (0.40) | CYP3A4GPBAR1PIK3CAKCNH2APP | |
| SCHEMBL31342865 | 0.83 | CYP3A4 (0.41) | CYP3A4PIK3CAKCNH2APP | |
| SCHEMBL31343044 | 0.82 | HCRTR1 (0.35) | CHRNB4CHRNA3KCNH2 | |
| Hydrochloric Acid SCHEMBL31342830 | 0.82 | SLC6A2 (0.40) | CHRNB4CHRNA3GPBAR1CCNT1CDK9 | |
| Hydrochloric Acid SCHEMBL31342985 | 0.82 | CYP3A4 (0.40) | CYP3A4GPBAR1PIK3CAKCNH2APP | |
| Hydrochloric Acid SCHEMBL31342849 | 0.82 | CYP3A4 (0.41) | CYP3A4PIK3CAKCNH2APP | |
| SCHEMBL31342926 | 0.82 | CYP3A4 (0.42) | CYP3A4CHRNB4CHRNA3GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049495-A1 | TERTIARY PYRIDYL AMINE MODULATORS OF CHOLESTEROL BIOSYNTHESIS AND THEIR USE FOR PROMOTING REMYLINATION | GENENTECH, INC. (US) | 2025-03-06 | — | — | WO | disclosed |