Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 7/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31342849 | 0.99 | CYP3A4 (0.41) | CYP3A4APPRPS6KA3CYP17A1PIK3CA | |
| SCHEMBL31342972 | 0.86 | HTR2C (0.43) | CYP3A4RPS6KA3HTR2CHTR6CYP2C9 | |
| SCHEMBL31343035 | 0.83 | CYP3A4 (0.40) | CYP3A4APPPIK3CAKCNH2SLC6A2 | |
| SCHEMBL31342875 | 0.83 | CYP3A4 (0.40) | CYP3A4APPPIK3CAKCNH2 | |
| Hydrochloric Acid SCHEMBL31342985 | 0.82 | CYP3A4 (0.40) | CYP3A4APPPIK3CAKCNH2SLC6A2 | |
| SCHEMBL31342964 | 0.82 | CYP3A4 (0.40) | CYP3A4APPPIK3CAKCNH2 | |
| SCHEMBL31342954 | 0.80 | CYP3A4 (0.45) | CYP3A4CYP17A1CYP2C9CYP2C19 | |
| SCHEMBL31342969 | 0.80 | HTR2C (0.39) | CYP3A4RPS6KA3CYP17A1HTR2CCYP2C9 | |
| Hydrochloric Acid SCHEMBL31343004 | 0.79 | HTR2C (0.40) | CYP3A4RPS6KA3CYP17A1HTR2CCYP2C9 | |
| SCHEMBL31342936 | 0.78 | CYP3A4 (0.54) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049495-A1 | TERTIARY PYRIDYL AMINE MODULATORS OF CHOLESTEROL BIOSYNTHESIS AND THEIR USE FOR PROMOTING REMYLINATION | GENENTECH, INC. (US) | 2025-03-06 | — | — | WO | disclosed |