Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 16/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31342935 | 0.88 | CYP3A4 (0.60) | CYP3A4MEN1KMT2A | |
| SCHEMBL31343092 | 0.88 | EPHX2 (0.49) | CYP3A4EPHX2 | |
| SCHEMBL31343012 | 0.87 | CYP3A4 (0.43) | CYP3A4MEN1KMT2A | |
| SCHEMBL31342921 | 0.86 | CYP3A4 (0.52) | CYP3A4MEN1KMT2A | |
| SCHEMBL31342880 | 0.86 | CYP3A4 (0.52) | CYP3A4MEN1KMT2A | |
| SCHEMBL31342826 | 0.84 | CYP3A4 (0.48) | CYP3A4 | |
| SCHEMBL31343031 | 0.83 | CYP3A4 (0.48) | CYP3A4 | |
| SCHEMBL31343001 | 0.83 | CYP3A4 (0.47) | CYP3A4 | |
| SCHEMBL31343078 | 0.83 | CYP3A4 (0.47) | CYP3A4 | |
| SCHEMBL31342948 | 0.82 | CYP3A4 (0.59) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049495-A1 | TERTIARY PYRIDYL AMINE MODULATORS OF CHOLESTEROL BIOSYNTHESIS AND THEIR USE FOR PROMOTING REMYLINATION | GENENTECH, INC. (US) | 2025-03-06 | — | — | WO | disclosed |