Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.48 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31342921 | 1.00 | CYP3A4 (0.52) | CYP3A4GPR119GPBAR1MEN1KMT2A | |
| SCHEMBL31342885 | 0.93 | MEN1 (0.52) | CYP3A4GPR119GPBAR1MEN1KMT2A | |
| SCHEMBL31342829 | 0.88 | GPR119 (0.43) | CYP3A4GPR119GPBAR1MEN1KMT2A | |
| SCHEMBL31343093 | 0.88 | GPR119 (0.52) | GPR119 | |
| SCHEMBL31343002 | 0.88 | GPR119 (0.52) | GPR119 | |
| SCHEMBL31342891 | 0.88 | CYP3A4 (0.53) | CYP3A4GPR119MEN1KMT2A | |
| SCHEMBL31342935 | 0.87 | CYP3A4 (0.60) | CYP3A4GPBAR1MEN1KMT2A | |
| SCHEMBL31342991 | 0.87 | GPR119 (0.45) | GPR119MEN1KMT2A | |
| SCHEMBL31342989 | 0.86 | GPR119 (0.44) | CYP3A4GPR119MEN1KMT2A | |
| SCHEMBL31342878 | 0.86 | CYP3A4 (0.51) | CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049495-A1 | TERTIARY PYRIDYL AMINE MODULATORS OF CHOLESTEROL BIOSYNTHESIS AND THEIR USE FOR PROMOTING REMYLINATION | GENENTECH, INC. (US) | 2025-03-06 | — | — | WO | disclosed |