Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | GPR6 | P46095 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31342834 | 0.90 | CYP3A4 (0.40) | CYP3A4GPR119NR1H2NR1H3GPR6 | |
| SCHEMBL31342779 | 0.87 | CYP3A4 (0.44) | CYP3A4GPR119GPBAR1 | |
| SCHEMBL31342866 | 0.86 | CYP3A4 (0.40) | CYP3A4HCRTR1HCRTR2GPR6 | |
| SCHEMBL31342949 | 0.85 | CYP3A4 (0.51) | CYP3A4GPR119GPBAR1 | |
| SCHEMBL31343028 | 0.85 | CYP3A4 (0.38) | CYP3A4GPR119NR1H2NR1H3 | |
| SCHEMBL31342929 | 0.81 | HCRTR1 (0.33) | CYP3A4HCRTR1HCRTR2HDAC6 | |
| SCHEMBL31342951 | 0.81 | CYP3A4 (0.41) | CYP3A4GPR119KCNH2GPR6 | |
| SCHEMBL31342923 | 0.79 | CYP3A4 (0.52) | CYP3A4GPR119GPR6 | |
| SCHEMBL31343044 | 0.79 | HCRTR1 (0.35) | KCNH2HCRTR1HCRTR2HDAC6 | |
| Hydrochloric Acid SCHEMBL31342858 | 0.78 | HCRTR1 (0.35) | KCNH2HCRTR1HCRTR2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049495-A1 | TERTIARY PYRIDYL AMINE MODULATORS OF CHOLESTEROL BIOSYNTHESIS AND THEIR USE FOR PROMOTING REMYLINATION | GENENTECH, INC. (US) | 2025-03-06 | — | — | WO | disclosed |