Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | GPR6 | P46095 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31343028 | 0.94 | CYP3A4 (0.38) | CYP3A4GPR119NR1H2NR1H3KIT | |
| SCHEMBL31342951 | 0.90 | CYP3A4 (0.41) | CYP3A4GPR119GPR6 | |
| SCHEMBL31342893 | 0.90 | CYP3A4 (0.39) | CYP3A4GPR119NR1H2NR1H3GPR6 | |
| SCHEMBL31342923 | 0.89 | CYP3A4 (0.52) | CYP3A4GPR119GPR6 | |
| SCHEMBL31342949 | 0.88 | CYP3A4 (0.51) | CYP3A4GPR119 | |
| SCHEMBL31342899 | 0.86 | NR1H2 (0.37) | CYP3A4GPR119NR1H2NR1H3KIT | |
| SCHEMBL31342995 | 0.86 | CYP3A4 (0.39) | CYP3A4GPR119KITGPR6 | |
| SCHEMBL31342779 | 0.85 | CYP3A4 (0.44) | CYP3A4GPR119 | |
| SCHEMBL31342993 | 0.83 | CYP3A4 (0.44) | CYP3A4 | |
| SCHEMBL31342917 | 0.83 | LMNA (0.41) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049495-A1 | TERTIARY PYRIDYL AMINE MODULATORS OF CHOLESTEROL BIOSYNTHESIS AND THEIR USE FOR PROMOTING REMYLINATION | GENENTECH, INC. (US) | 2025-03-06 | — | — | WO | disclosed |