SCHEMBL31343370

SCHEMBL31343370

CC(C)Nc1cc(Cl)nc2c1ccn2COCC[Si](C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 1/20 0.32
DGAT1 O75907 2/20 0.32
CDK2 P24941 1/20 0.30
F11 P03951 1/20 0.30
NPC1 O15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22252858 1.00 NR4A2 (0.32) NR4A2DGAT1CDK2F11NPC1
SCHEMBL31343279 0.89 CDC7 (0.35) DGAT1CDK2F11NPC1
SCHEMBL22252549 0.89 CDC7 (0.35) DGAT1CDK2F11NPC1
SCHEMBL22252732 0.87 DGAT1 (0.33) DGAT1NPC1
SCHEMBL31343229 0.87 DGAT1 (0.33) DGAT1NPC1
SCHEMBL22252745 0.87 TLR7 (0.32) DGAT1
SCHEMBL31343197 0.87 TLR7 (0.32) DGAT1
SCHEMBL22252742 0.85 DGAT1 (0.33) DGAT1NPC1
SCHEMBL31343232 0.85 DGAT1 (0.33) DGAT1NPC1
SCHEMBL22252547 0.83 DGAT1 (0.32) NR4A2DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113557237-B Pyrrolopyridine derivatives and their use for preventing or treating protein kinase related diseases 沃若诺伊公司 2025-01-14 CN disclosed