Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | PPOX | P50336 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | LIPE | Q05469 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23356328 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2AMRGPRX4MEN1TTR | |
| SCHEMBL23356302 | 0.86 | KMT2A (0.47) | SMN1; SMN2KMT2AMRGPRX4LMNALIPE | |
| SCHEMBL23356251 | 0.85 | SMN1; SMN2 (0.52) | SMN1; SMN2KMT2AMEN1LMNALIPE | |
| SCHEMBL31344059 | 0.85 | SMN1; SMN2 (0.52) | SMN1; SMN2KMT2AMEN1LMNALIPE | |
| SCHEMBL23356327 | 0.83 | KMT2A (0.53) | SMN1; SMN2KMT2AATM | |
| SCHEMBL29737621 | 0.83 | KMT2A (0.53) | SMN1; SMN2KMT2AATM | |
| SCHEMBL23356260 | 0.82 | KMT2A (0.51) | SMN1; SMN2KMT2AATM | |
| SCHEMBL23356277 | 0.82 | KMT2A (0.51) | SMN1; SMN2KMT2AATM | |
| SCHEMBL23356237 | 0.82 | KMT2A (0.51) | SMN1; SMN2KMT2AATM | |
| SCHEMBL23356257 | 0.82 | KMT2A (0.51) | SMN1; SMN2KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112689633-B | For inhibiting Nav1.8 Pyridinecarboxamide Compounds | 利伯研究所公司 | 2025-01-24 | — | — | CN | disclosed |