Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK1 | Q13153 | 3/20 | 0.56 |
| ▸ | TNIK | Q9UKE5 | 7/20 | 0.54 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.53 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.52 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.52 |
| ▸ | CLK1 | P49759 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.49 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.49 |
| ▸ | MAP3K11 | Q16584 | 3/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28829877 | 0.92 | PAK1 (0.54) | PAK1TNIKPKN1CAMKK2MAP4K1 | |
| SCHEMBL29767435 | 0.92 | PAK1 (0.54) | PAK1TNIKPKN1CAMKK2MAP4K1 | |
| SCHEMBL29767442 | 0.92 | PAK1 (0.54) | PAK1TNIKPKN1CAMKK2MAP4K1 | |
| SCHEMBL28587404 | 0.84 | AXL (0.62) | PAK1TNIKPKN1CAMKK2MAP4K1 | |
| SCHEMBL21592629 | 0.82 | MAP4K1 (0.66) | TNIKCAMKK2MAP4K1CLK1DYRK1A | |
| SCHEMBL28597666 | 0.82 | MAP4K1 (0.73) | PAK1TNIKPKN1CAMKK2MAP4K1 | |
| SCHEMBL31553248 | 0.82 | PAK1 (0.51) | PAK1TNIKPKN1MAP4K1MAP3K11 | |
| SCHEMBL28769119 | 0.82 | PAK1 (0.51) | PAK1TNIKPKN1MAP4K1MAP3K11 | |
| SCHEMBL28769141 | 0.81 | PAK1 (0.61) | PAK1TNIKPKN1MAP4K1MAP3K11 | |
| SCHEMBL29767434 | 0.81 | PAK1 (0.61) | PAK1TNIKPKN1MAP4K1MAP3K11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685489-B | Polysubstituted nitrogen-containing heterocyclic compound and application thereof | 南京再明医药有限公司 | 2025-03-07 | — | — | CN | disclosed |