SCHEMBL31344633

SCHEMBL31344633

CC1(C)CCC(CN2CCN(c3ccc(C(=O)NS(=O)(=O)c4ccc(NC5CCN(S(C)(=O)=O)CC5)c([N+](=O)[O-])c4)c(Oc4cnc5[nH]ccc5c4)c3)CC2)=C(c2ccc(Cl)cc2)C1

nearest known ligand 0.89

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ BCL2 P10415 19/20 0.89

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1699823 1.00 BCL2 (0.89) BCL2
SCHEMBL30313998 0.97 BCL2 (0.89) BCL2
SCHEMBL1699864 0.97 BCL2 (0.89) BCL2
SCHEMBL1699815 0.95 BCL2 (0.90) BCL2
SCHEMBL30313973 0.95 BCL2 (0.90) BCL2
SCHEMBL30314219 0.95 BCL2 (0.93) BCL2
SCHEMBL1699848 0.95 BCL2 (0.93) BCL2
SCHEMBL1699841 0.95 BCL2 (0.95) BCL2
SCHEMBL30313887 0.95 BCL2 (0.95) BCL2
SCHEMBL31344645 0.95 BCL2 (0.92) BCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4682148-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2026-01-21 — — EP disclosed
EP-4474383-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2024-12-11 — — EP disclosed
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