SCHEMBL31344636

SCHEMBL31344636

CC1(C)CCC(CN2CCN(c3ccc(C(=O)NS(=O)(=O)c4ccc(OCC5(F)CCN(C6COC6)CC5)c(Cl)c4)c(Oc4cnc5[nH]ccc5c4)c3)CC2)=C(c2ccc(Cl)cc2)C1

nearest known ligand 0.86

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ BCL2 P10415 20/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1701487 1.00 BCL2 (0.86) BCL2
SCHEMBL30314057 0.94 BCL2 (0.88) BCL2
SCHEMBL30313914 0.94 BCL2 (0.83) BCL2
SCHEMBL1700704 0.94 BCL2 (0.83) BCL2
SCHEMBL1700612 0.94 BCL2 (0.88) BCL2
SCHEMBL30467947 0.94 BCL2 (0.88) BCL2
SCHEMBL1700548 0.94 BCL2 (0.88) BCL2
SCHEMBL1700452 0.93 BCL2 (0.89) BCL2
SCHEMBL30467973 0.93 BCL2 (0.89) BCL2
SCHEMBL1700600 0.93 BCL2 (0.88) BCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4682148-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2026-01-21 — — EP disclosed
EP-4474383-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2024-12-11 — — EP disclosed
Send feedback