SCHEMBL30467973

SCHEMBL30467973

CC1(C)CCC(CN2CCN(c3ccc(C(=O)NS(=O)(=O)c4ccc(OCC5(F)CCOCC5)c(Cl)c4)c(Oc4cnc5[nH]ccc5c4)c3)CC2)=C(c2ccc(Cl)cc2)C1

nearest known ligand 0.89

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ BCL2 P10415 20/20 0.89
▸ BCL2L1 Q07817 1/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1700452 1.00 BCL2 (0.89) BCL2BCL2L1
SCHEMBL30467925 0.94 BCL2 (0.88) BCL2
SCHEMBL1700600 0.94 BCL2 (0.88) BCL2
SCHEMBL31344618 0.94 BCL2 (1.00) BCL2BCL2L1
SCHEMBL1701566 0.94 BCL2 (1.00) BCL2BCL2L1
SCHEMBL30313804 0.94 BCL2 (0.91) BCL2BCL2L1
SCHEMBL523310 0.94 BCL2 (0.91) BCL2BCL2L1
SCHEMBL30467899 0.94 BCL2 (1.00) BCL2BCL2L1
SCHEMBL1701691 0.94 BCL2 (1.00) BCL2BCL2L1
SCHEMBL30468093 0.94 BCL2 (1.00) BCL2BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4682148-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2026-01-21 — — EP disclosed
EP-4474383-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2024-12-11 — — EP disclosed
EP-4218731-A2 MELT-EXTRUDED SOLID DISPERSIONS CONTAINING AN APOPTOSIS-INDUCING AGENT AbbVie Ireland Unlimited Company (IE) 2023-08-02 — — EP disclosed
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